GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs13096604 | chr3:134250099 | ANAPC13 | chr3:134196547-134204865:- | -0.5 | -7.96 | 2.01E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs13096604 | chr3:134250099 | CEP63 | chr3:134204575-134293852:+ | -0.24 | -4.2 | 3.39E-5 | Height |
| BLCA | cis | rs7611238 | 1 | rs13096715 | chr3:195074488 | C3orf21 | chr3:194789015-194991895:- | 0.28 | 5.47 | 8.34E-8 | Body mass index |
| BLCA | cis | rs7655841 | 1 | rs13109003 | chr4:129975969 | C4orf33 | chr4:130014829-130033842:+ | -0.32 | -5.26 | 2.42E-7 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs7655841 | 1 | rs13130762 | chr4:130022875 | C4orf33 | chr4:130014829-130033842:+ | -0.33 | -5.42 | 1.04E-7 | Chronic obstructive pulmonary disease (moderate to severe) |
| BLCA | cis | rs1109501 | 1 | rs13148900 | chr4:71361114 | AMTN | chr4:71384298-71398459:+ | -0.25 | -3.95 | 9.39E-5 | Alcoholism (heaviness of drinking) |
| BLCA | cis | rs1109114 | 1 | rs13161048 | chr5:148615269 | AFAP1L1 | chr5:148651401-148721365:+ | -0.25 | -4.63 | 4.99E-6 | Body mass index |
| BLCA | cis | rs7927771 | 1 | rs1317149 | chr11:47486885 | C1QTNF4 | chr11:47611216-47615961:- | -0.28 | -5.36 | 1.42E-7 | Subjective well-being |
| BLCA | cis | rs1577917 | 1 | rs13194429 | chr6:86646705 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.5 | 2.25E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs41266839 | 1 | rs13195401 | chr6:26463574 | BTN3A2 | chr6:26365398-26378546:+ | -0.73 | -7.89 | 3.1E-14 | Schizophrenia |
| BLCA | cis | rs41266839 | 1 | rs13195402 | chr6:26463575 | BTN3A2 | chr6:26365398-26378546:+ | -0.73 | -7.89 | 3.1E-14 | Schizophrenia |
| BLCA | cis | rs1577917 | 1 | rs13196930 | chr6:86652245 | SNHG5 | chr6:86386726-86388451:- | -0.54 | -9.53 | 1.9E-19 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs13199006 | chr6:86608708 | SNHG5 | chr6:86386726-86388451:- | -0.55 | -10.04 | 3.34E-21 | Response to antipsychotic treatment |
| BLCA | cis | rs853679 | 1 | rs13200462 | chr6:28218199 | ZNF389 | chr6:28129551-28137375:+ | -0.33 | -4.07 | 5.63E-5 | Depression |
| BLCA | cis | rs11976180 | 1 | rs1320893 | chr7:143752112 | ARHGEF35 | chr7:143883677-143892736:- | -0.33 | -5.82 | 1.26E-8 | Obesity-related traits |